Figure 1

PKA subunit overexpression in human ovarian cancer cells (OVCAR8). 1A. Northern blot analysis of transfectants: parental cells, vector only, Cα PKA catalytic subunit, RIα, RIIα, RIIβ regulatory subunits as indicated. 1B. Western blot analysis – same transfectants. 1C. OVCAR 8 parental cells in culture. 1D. RIα-transfected cells in culture. 1E. RIIβ-transfected cells in culture. 1F. Growth response curves for PKA subunit transfectants.