Figure 3From: Gene expression in BMPR2 mutation carriers with and without evidence of Pulmonary Arterial Hypertension suggests pathways relevant to disease penetrance GTP-related genes have large numbers of differentially regulated genes in all patient samples (registry # is outside of each circle). Increasing numbers of patients increases the significance of the ontology group, but produces decreasing numbers of genes changed in all patients. For instance, patient #723 and #266 have 25 GTP-related genes in common; this drops to 14 when overlap with patient #264 is added.Back to article page