Table 3 Methylation status using COBRA of the 10 highest-ranking gene promoters.
From: Discovery of DNA methylation markers in cervical cancer using relaxation ranking
Rank | Gene symbol | Profile X-Y-Z | Chromosomal location | Methylation in cancer | Methylation in normal |
|---|---|---|---|---|---|
1 | DAZL | 1-1-13 | 3p24.3 | 9/9 | 5/5 |
2 | ADARB1 | 1-2-15 | 21q22.3 | Nd | Nd |
3 | SYCP3 | 0-1-12 | 12q | 9/9 | 5/5 |
4 | AUTS2 | 12-0-12 | 7q11.22 | 0/9 | 0/5 |
5 | NNAT | 0-1-11 | 20q11.2 | 9/9 | 5/5 |
6 | SST | 1-1-12 | 3q28 | 7/9 | 0/5 |
7 | HTRA3 | 6-0-10 | 4p16.1 | 1/9 | 0/5 |
8 | ZFP42 | 11-1-14 | 4q35.2 | 9/9 | 5/5 |
9 | NPTX1 | 2-3-14 | 17q25.1 | 5/10 | 0/5 |
10 | GDA | 14-3-15 | 9q21.13 | 0/9 | 0/5 |
47 | CCNA1 | 3-0-7 | 13q12.3-q13 | 6/10 | 0/5 |