Table 6 Pterostilbene-responsive genes involved in sulfur metabolism and/or assimilation
Accession | Gene | Ratio | p-value | Gene Description |
|---|---|---|---|---|
a. Methionine metabolism | ||||
   YJR137C | ECM17 | -2.5 | 2.48 × 10-5 | Sulfite reductase beta subunit |
   YKR069W | MET1 | -3.1 | 3.88 × 10-4 | AdoMet-dependent uroporphyrinogen III transmethylase |
   YJR010W | MET3 | -3.8 | 3.5 × 10-4 | ATP sulfurylase |
   YER091C | MET6 | -2.4 | 8.83 × 10-5 | Cobalamin-independent methionine synthase |
   YFR030W | MET10 | -2.1 | 1.5 × 10-3 | Sulfite reductase alpha subunit |
   YGL125W | MET13 | -3.6 | 1.46 × 10-4 | Methylenetetrahydrofolate reductase |
   YKL001C | MET14 | -3.1 | 1.12 × 10-3 | Adenylylsulfate kinase |
   YPR167C | MET16 | -2.0 | 7.56 × 10-4 | 3'-phosphoadenylylsulfate reductase |
   YOL064C | MET22 | -2.5 | 1.68 × 10-4 | Bisphosphate-3'-nucleotidase, |
   YLL062C | MHT1 | -3.4 | 6.69 × 10-4 | S-methylmethionine-homocysteine methyltransferase |
   YLR180W | SAM1 | -2.1 | 6.39 × 10-5 | S-adenosylmethionine synthetase |
b. Sulfur and aspartate family amino acid metabolic processes (in addition to a) | ||||
   YNL103W | MET4 | 3.0 | 4.01 × 10-4 | Leucine zipper transcriptional activator |
   YPL038W | MET31 | 2.2 | 2.45 × 10-3 | Transcriptional regulator highly homologous to Met32p |
   YJR130C | STR2 | 2.3 | 2.97 × 10-3 | Cystathionine gamma-synthase |
   YGL184C | STR3 | -3.6 | 4.1 × 10-3 | Cystathionine beta-lyase |
   YJR060W | CBF1 | -3.0 | 1.11 × 10-3 | Basic helix-loop-helix protein |
   YHR025W | THR1 | -2.2 | 2.05 × 10-4 | Homoserine kinase |
c. All other genes affected under the term "sulfur metabolism" | ||||
   YLL060C | GTT2 | 2.5 | 8.23 × 10-4 | Glutathione transferase |
   YEL017W | GTT3 | -2.2 | 6.72 × 10-4 | Protein with a possible role in glutathione metabolism |
   YGR286C | BIO2 | -3.0 | 9.79 × 10-4 | Biotin synthase |
   YJL212C | OPT1 | -2.5 | 1.8 × 10-4 | Peptide transporter/glutathione transporter |
   YLL057C | JLP1 | 13.5 | 6.93 × 10-4 | Fe(II)-dependent sulfonate/α-ketoglutarate dioxygenase |
   YLR043C | TRX1 | -2.1 | 6.95 × 10-5 | Cytoplasmic thioredoxin |
d. Sulfur uptake | ||||
   YBR294W | SUL1 | -5.53 | 4.64 × 10-5 | Sulfate uptake (transporter) |
   YLR092W | SUL2 | -2.75 | 1.89 × 10-4 | High affinity sulfate permease |