Table 1 Information on biological processes based on Gene ontology.
From: Genomics and proteomics approaches to the study of cancer-stroma interactions
Biological Process | Down-regulated genes |
|---|---|
Cell communication | Â |
   signal transduction | FAS, SQSTM1, YWHAZ |
Transcription | ARID4A, CALR, MYC, PARP1, RNF10, SQSTM1 |
Translation | AARS, RPLP0, RPS17, RPS23 |
Apoptosis | CALR |
   induction | FAS |
   anti-apoptosis | TPT1, YWHAZ |
Cell migration | TMSB4X |
Cell cycle | DYNC1H1, MYC, PSMC6 |
Cell proliferation | Â |
   negative regulation | GPNMB, LDOC1 |
   positive regulation | MYC |
Developmental process | Â |
   epidermis development | UGCG |
Response to stimulus | Â |
   defense response |  |
inflammatory response | LTA4H |
   response to stress | EIF2AK1, SQSTM1 |
response to oxidative stress | Â |
   response to external stimulus | EIF2AK1 |
Transport | CALR, NDUFA4, SQSTM1 |
Metabolic process | COX7C, OLA1, |
   protein metabolic process | PARP1, SQSTM1, USP9X |
protein modification process | GRPEL2, HSP90AB1, PPP2R2A, PRPF4B, USP48 |
   lipid metabolic process | LTA4H, UGCG |
   DNA repair | PARP1 |
   RNA processing | PRPF4B, SF3B1 |
Cellular homeostasis | CALR, MYC, RPS17 |
No classification | GNB2L1, RCN1 |
| Â | Up-regulated genes |
Transcription | ENO1 |
Translation | EIF1, TARS |
Apoptosis | RTN3 |
   induction | DAP3 |
Cell proliferation | PRDX1 |
   negative regulation | ENO1 |
Developmental process | Â |
   organ development | PRDX1 |
Response to stimulus | Â |
   response to stress | EIF1, RTN3 |
Metabolic process | PRDX1 |
   protein metabolic process |  |
protein modification process | P4HB |
   nucleic acid metabolic process |  |
RNA processing | USP39 |