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Table 2 The most highly significant canonical pathway assignments for the set of smoking-correlated genes

From: Transcriptomic epidemiology of smoking: the effect of smoking on gene expression in lymphocytes

Canonical pathway

P-value

Number of genes

Natural killer cell signaling

7.9 Ă— 10-7

11

CTLA4 Signaling in cytotoxic T lymphocytes

1.2 Ă— 10-4

8

SAPK/JNK signaling

5.7 Ă— 10-3

6

Xenobiotic metabolism signaling

5.9 Ă— 10-3

10

Metabolism of xenobiotics by cytochrome P450

9.6 Ă— 10-3

4