Skip to main content
Figure 2 | BMC Medical Genomics

Figure 2

From: Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks

Figure 2

Method of coding the polymorphisms in the database. The code assigned to the polymorphisms transformed each polymorphism in three genotype classes: major homozygous, heterozygous and minor homozygous. For each class a binary coding was applied: 0 if variable absent; 1 if variable present. So for example considering the polymorphism MTRR 66A>G which can exist in three variants: AA (major homozygous), AG (heterozygous) and GG (minor homozygous). Supposing that three records are AA, GG and AG, the coding has been applied as shown in the figure.

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us