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Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2

  • Tú Nguyen-Dumont1,
  • Lars P Jordheim2,
  • Jocelyne Michelon1,
  • Nathalie Forey1,
  • Sandrine McKay-Chopin1,
  • Kathleen Cuningham Foundation Consortium for Research into Familial Aspects of Breast Cancer (kConFab)3,
  • Olga Sinilnikova4,
  • Florence Le Calvez-Kelm1,
  • Melissa C Southey5,
  • Sean V Tavtigian6 and
  • Fabienne Lesueur1Email author
BMC Medical Genomics20114:39

DOI: 10.1186/1755-8794-4-39

Received: 22 July 2010

Accepted: 11 May 2011

Published: 11 May 2011

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
22 Jul 2010 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
Resubmission - Version 3
Submitted Manuscript version 3
23 Jul 2010 Author responded Author comments - Fabienne Lesueur
Resubmission - Version 4
23 Jul 2010 Submitted Manuscript version 4
23 Aug 2010 Reviewed Reviewer Report - Ana-Teresa Maia
3 Sep 2010 Reviewed Reviewer Report - David De Koeyer
Resubmission - Version 5
Submitted Manuscript version 5
3 Nov 2010 Reviewed Reviewer Report - Ana-Teresa Maia
16 Nov 2010 Reviewed Reviewer Report - David De Koeyer
21 Dec 2010 Author responded Author comments - Fabienne Lesueur
Resubmission - Version 6
21 Dec 2010 Submitted Manuscript version 6
28 Jan 2011 Author responded Author comments - Fabienne Lesueur
Resubmission - Version 7
28 Jan 2011 Submitted Manuscript version 7
Resubmission - Version 8
Submitted Manuscript version 8
Resubmission - Version 9
Submitted Manuscript version 9
15 Apr 2011 Author responded Author comments - Fabienne Lesueur
Resubmission - Version 10
15 Apr 2011 Submitted Manuscript version 10
Publishing
11 May 2011 Editorially accepted
11 May 2011 Article published 10.1186/1755-8794-4-39

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Genetic Cancer Susceptibility Group, IARC
(2)
INSERM U590, Université Lyon 1
(3)
Peter MacCallum Cancer Center
(4)
Unité Mixte de Génétique Constitutionnelle des Cancers Fréquents, Hospices Civils de Lyon, Centre Léon Bérard
(5)
Department of Pathology, The University of Melbourne
(6)
Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah

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