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Table 2 Summary of the sense and AFAS transcripts that showed different levels of expression in cancer tissues and in normal tissues

From: Comprehensive expressional analyses of antisense transcripts in colon cancer tissues using artificial antisense probes

  

AFAS probes

Corresponding

sense genes

All

2376

(100%)

501

(100%)

AFAS Expression level ≥100

in normal tissue (dT)

213

(9%)

153

(31%)

 

in cancer tissue (dT)

183

(8%)

138

(28%)

 

in normal tissue (Random)

931

(39%)

392

(78%)

 

in cancer tissue (Random)

908

(38%)

388

(77%)

AFAS expression change in cancer tissue

Cancer ≥ Normal×2 (Random)

71

(3%)

56

(11%)

 

Normal ≥ Cancer×2 (Random)

101

(4%)

87

(17%)

Sense-AFAS pair

having altered expression balance

Sense up, AFAS down (Random)

44

(2%)

39

(8%)

 

Sense down, AFAS up (Random)

5

(0%)

5

(1%)

 

Sense up (dT), AFAS down (Random)

24

(1%)

17

(3%)

 

Sense down (dT), AFAS up (Random)

22

(1%)

16

(3%)

  1. Expression levels for "Expression level ≥ 100" and "Expression increased by" were calculated based on median expression levels among patients for each probe.