From: Genome wide association study identifies KCNMA1contributing to human obesity
 |  |  |  | obese cases |  |  | lean and population-based controls | ||
---|---|---|---|---|---|---|---|---|---|
 | Cohort | SNP§ | Nationality | female/male | BMI* (kg/m2) | age* (years) | female/male | BMI* (kg/m2) | age* (years) |
Discovery | 1 | 406,177 | Swedish | 131/33§ | 44.7 ± 4.7 | 43.8 ± 12.6 | 137/26 | 22.2 ± 1.8 | 51.6 ± 6.1 |
Replication | 2 | 700 | Swedish | 370/90§§ | 44.6 ± 4.6 | 42.2 ± 13.2 | 206/41 | 22.6 ± 1.7 | 51.6 ± 5.3 |
Replication | 3 | 21 | Swedish | 1025/789 | 37.1 ± 5.4 | 46.6 ± 11.4 | 819/885 | 22.8 ± 1.7 | 48.7 ± 10.8 |
Replication | 4** | 21 | French | 641/344 | 33.7 ± 8.2 | 14.1 ± 5.0 | 289/243# | 18.7 ± 3.3 | 11.8 ± 1.6 |
Replication | 5 | 2 | French | 682/246 | 48.5 ± 7.6 | 43.0 ± 12.1 | 1630/1108# | 23.8 ± 3.5 | 49.7 ± 6.3 |
Replication | 6** | 2 | German | 278/209 | 33.4 ± 6.8 | 14.4 ± 3.7 | 271/171 | 18.3 ± 1.1 | 16.1 ± 5.8 |
Total | Â | Â | Â | 3127/1711 | Â | Â | 3353/2474 | Â | Â |