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Figure 4 | BMC Medical Genomics

Figure 4

From: Integrating Factor Analysis and a Transgenic Mouse Model to Reveal a Peripheral Blood Predictor of Breast Tumors

Figure 4

Inclusion probabilities of factors in the predictive model. We generated a collection of 26 factors from the human PBMC training set using the methods described previously and used SSS to put these together in various combinations to form predictive models (5000 iterations), which were validated in an independent sample set. We calculated the top performing factors based on their inclusion probability (median posterior marginal probability) in the top 200 models. These 26 factors are plotted along the x-axis and the median posterior marginal probabilities are plotted on the y-axis. The top 3 factors with inclusion probabilities significantly above the background noise are 3, 12 and 14.

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