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Figure 2 | BMC Medical Genomics

Figure 2

From: Targeted high throughput sequencing in clinical cancer Settings: formaldehyde fixed-paraffin embedded (FFPE) tumor tissues, input amount and tumor heterogeneity

Figure 2

Different DNA amounts for targeted re-sequencing approaches. (A) Exonwise coverage comparisons obtained with different amounts of input DNA. Coefficient of variations were calculated for each comparison and plotted by the smallest coverage of each exon-exon comparison. (B) Variant/Reference ratio distribution for different amounts of input DNA. Depicted is the density curve for each preparation and distribution. (C) Comparison of SNVs detected with different amounts of input DNA. The Y-axis depicts the percentage of foci in concordance for different preparations at different coverage levels. (D) Comparison of InDels detected with different amounts of input DNA. The y-axis depicts the percentage of foci in concordance for different preparations at different coverage levels.

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BMC Medical Genomics

ISSN: 1755-8794

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