Batch correction of microarray data substantially improves the identification of genes differentially expressed in Rheumatoid Arthritis and Osteoarthritis

Table 2 Sample features (incl. acquiry date) and clinical diagnosis of RA and OA patients

Batch	Acquiry date	Sample ID	Treatment	Diagnosis
1	2006-04-07	EB87.TGF.0 h	TGF-β1	RA
1	2006-04-07	EB87.TNF.0 h	TNF-α	RA
2	2006-11-30	EB190.TGF.0 h	TGF-β1	OA
2	2006-11-30	EB190.TNF.0 h	TNF-α
3	2006-12-07	EB202.TGF.0 h	TGF-β1
		EB202.TNF.0 h	TNF-α
		EB205.TGF.0 h	TGF-β1
		EB205.TNF.0 h	TNF-α
4	2006-12-12	EB220.TGF.0 h	TGF-β1	RA
		EB220.TNF.0 h	TNF-α
		EB221.TGF.0 h	TGF-β1
		EB221.TNF.0 h	TNF-α
5	2009-03-04	EB173.TGF.0 h	TGF-β1	OA
		EB173.TNF.0 h	TNF-α	OA
		EB227.TGF.0 h	TGF-β1	RA
		EB227.TNF.0 h	TNF-α	RA
6	2009-03-14	EB194.TGF.0 h	TGF-β1	OA
		EB194.TNF.0 h	TNF-α	OA
		EB213.TGF.0 h	TGF-β1	RA
		EB213.TNF.0 h	TNF-α
7	2009-03-26	EB88.TGF.0 h	TGF-β1
		EB88.TNF.0 h	TNF-α
		EB168.TGF.0 h	TGF-β1	OA
		EB168.TNF.0 h	TNF-α

All samples (total 120 arrays) were derived from 5 different time points of the respective stimulation experiment. Batch = Integer label for the Batch Correction; Acquiry date = date of hybridization of the microarray; Sample ID = unique array identification; Stimulation = Stimulation of the samples; Diagnosis = Disease of the patient.

ISSN: 1755-8794