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Figure 1 | BMC Medical Genomics

Figure 1

From: Polymorphism in glutamate cysteine ligase catalytic subunit (GCLC) is associated with sulfamethoxazole-induced hypersensitivity in HIV/AIDS patients

Figure 1

Pathways of SMX metabolism, bio-activation and detoxification, and pathway of GSH biosynthesis. NAT1/2, N-acetyltransferase 1 and 2; 2C9, cytochrome p450 2C9; MPO, myeloperoxidase; PTGS, prostaglandin-endoperoxide synthase; FMO, flavin containing monooxygenase; Cyb5R, NADH-cytochrome b5/cytochrome b5 reductase complex; GSH, glutathione; GCL, glutamate-cystein ligase, including catalytic and regulatory subunits GCLC and GCLM; GSS, glutathione synthetase.

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BMC Medical Genomics

ISSN: 1755-8794

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