Table 2 Amplicons and p53 alterations according to array CGH clusters and G2I classes of tumors (%)
All | Array CGH clusters | G2I classes | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
a | b | c | d | e | f | 1 | 2 | 3 | ||
Total tumors | 135 | 34 | 25 | 16 | 13 | 35 | 12 | 19 | 88 | 28 |
Tumors with amplicons | 64 (47) | 14 (41) | 8 (32) | 10 (63) | 7 (54) | 17 (49) | 8 (67) | 3 (16) | 41 (47) | 20 (71) |
Amplicons | 296 | 60 | 43 | 37 | 24 | 69 | 63 | 6 | 173 | 117 |
Amplicons per tumor (mean) | 2.2 | 1.8 | 1.7 | 2.3 | 1.8 | 2.0 | 5.3 | 0.3 | 2.0 | 4.2 |
Amplicons per tumor in tumors with amplicons (mean) | 4.6 | 4.3 | 5.4 | 3.7 | 3.4 | 4.1 | 7.9 | 2 | 4.2 | 5.9 |
5q23.3 (a) | 7 (5) | 2 ( 6) | 3 (12) | 0 | 0 | 2 ( 6) | 0 | 0 | 5 (6) | 2 (7) |
8p12a or 8p12-p11 | 11 (8) | 2 (6) | 1 (4) | 2 (8) | 3 (23) | 2 ( 6) | 1 (8) | 0 | 8 (9) | 3 (11) |
11q13.2-q13.3 | 18 (13) | 4 (12) | 1 (4) | 2 (8) | 0 | 8 (23) | 3 (25) | 1 (5) | 9 (10) | 8 (29) |
11q14.1a | 11 (8) | 3 (9) | 0 | 2 (13) | 0 | 5 (14) | 1 (8) | 1 (5) | 7 (8) | 3 (11) |
12q13.11-q13.12 | 7 (5) | 1 (3) | 1 (4) | 0 | 0 | 3 (9) | 2 (17) | 0 | 4 (5) | 3 (11) |
17q11.2b | 6 (4) | 1 (3) | 1 (4) | 0 | 0 | 2 (6) | 2 (17) | 0 | 3 (3) | 3 (11) |
17q12e | 17 (3) | 4 (12) | 3 (12) | 1 (4) | 4 (31) | 4 (11) | 1 (8) | 1 (5) | 12 (14) | 4 (14) |
17q21.1-q21.2 | 8 (6) | 2 (6) | 2 (8) | 0 | 2 (15) | 2 (6) | 0 | 1 (5) | 5 (6) | 2 (7) |
17q21.31 | 8 (6) | 1 (3) | 0 | 1 (6) | 2 (15) | 3 (9) | 1 (8) | 1 (5) | 5 (6) | 2 (7) |
17q21.33 | 8 (6) | 1 (3) | 0 | 1 (6) | 2 (15) | 2 (6) | 2 (7) | 0 | 4 (5) | 4 (14) |
20q (b) | 11 (8) | 3 (9) | 1 (4) | 0 | 0 | 3 (9) | 4 (33) | 0 | 5 (6) | 6 (21) |
p53 alteration (c) | 39 (29) | 11 (32) | 5 (17) | 5 (31) | 4 (31) | 7 (20) | 7 (58) | 0 | 24 (27) | 15 (54) |