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Table 2 Enriched Go terms of differentially expressed proteins in mitochondria of metastatic 5-8F relative to non-metastatic 6-10B cells

From: Mitochondrial proteomics of nasopharyngeal carcinoma metastasis

GO-ID

Description

P-Value

Genes

Biological Process

34614

Cellular response to reactive oxygen species

7.09E-6

PRDX6↑, PRDX3↑, SOD2↑

42743

Hydrogen peroxide metabolic process

2.39E-6

PRDX6↑, PRDX3↑, SOD2↑

51881

Regulation of mitochondria membrane potential

5.62E-5

PRDX3↑, SOD2↑

45454

Cell redox homeostasis

3.92E-5

PRDX6↑, PDIA5↑, PRDX3↑

55114

Oxidation reduction

2.92E-5

PRDX6↑, IDH3B↓, PDIA5↑, PRDX3↑, ETFA↑, SOD2↑

Molecular Function

16491

Oxidoreductase activity

2.64E-6

PRDX6↑, IDH3B↓, PDIA5↑, PRDX3↑, COX5A↓, ETFA ↑, SOD2↑

43027

Caspase inhibitor activity

6.61E-5

PRDX6↑, PRDX3↑

51920

Peroxiredoxin activity

1.51E-5

PRDX6↑, PRDX3↑

15288

Porin activity

1.51E-5

VDAC2↑, VDAC1↑

16209

Antioxidant activity

1.35E-5

PRDX6↑, PRDX3↑, SOD2↑

  1. ↑ : up- regulated expression in metastatic 5-8F cells relative to non-metastatic 6-10B cells.
  2. ↓ : down-regulated expression in metastatic 5-8F cells relative to non-metastaic 6-10B cells.