Table 6 Ten most up-regulated pathways by insulin in the insulin-resistant group
GO category | Pathway name | Nominal p | Permuted p |
|---|---|---|---|
GO:0016125 | sterol metabolic process | 1.52E-08 | 0.0001 |
GO:0006629 | lipid metabolic process | 2.31E-08 | 0.0001 |
GO:0008203 | cholesterol metabolic process | 1.12E-07 | 0.0001 |
GO:0044255 | cellular lipid metabolic process | 1.36E-07 | 0.0001 |
GO:0008202 | steroid metabolic process | 6.34E-07 | 0.0001 |
GO:0016126 | sterol biosynthetic process | 4.45E-06 | 0.0002 |
GO:0006694 | steroid biosynthetic process | 4.93E-06 | 0.0001 |
GO:0001889 | liver development | 6.62E-06 | 0.0002 |
GO:0008015 | blood circulation | 1.00E-05 | 0.0002 |
GO:0042127 | regulation of cell proliferation | 1.77E-05 | 0.0006 |