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Multilocus loss of DNA methylation in individuals with mutations in the histone H3 Lysine 4 Demethylase KDM5C

  • Daria Grafodatskaya1,
  • Barian HY Chung2, 3,
  • Darci T Butcher1,
  • Andrei L Turinsky4,
  • Sarah J Goodman3,
  • Sana Choufani3,
  • Yi-An Chen1,
  • Youliang Lou1,
  • Chunhua Zhao1,
  • Rageen Rajendram1,
  • Fatima E Abidi5,
  • Cindy Skinner5,
  • James Stavropoulos6,
  • Carolyn A Bondy7,
  • Jill Hamilton8, 9,
  • Shoshana Wodak4, 10,
  • Stephen W Scherer10, 11,
  • Charles E Schwartz5 and
  • Rosanna Weksberg2, 9Email author
Contributed equally
BMC Medical Genomics20136:1

DOI: 10.1186/1755-8794-6-1

Received: 2 October 2012

Accepted: 14 January 2013

Published: 28 January 2013

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Open Peer Review reports

Pre-publication versions of this article and author comments to reviewers are available by contacting info@biomedcentral.com.

Original Submission
2 Oct 2012 Submitted Original manuscript
Resubmission - Version 2
Submitted Manuscript version 2
28 Aug 2012 Author responded Author comments - Rosanna Weksberg
Resubmission - Version 3
28 Aug 2012 Submitted Manuscript version 3
2 Oct 2012 Author responded Author comments - Rosanna Weksberg
Resubmission - Version 4
2 Oct 2012 Submitted Manuscript version 4
20 Nov 2012 Reviewed Reviewer Report - Cintia Santos-Rebouças
12 Dec 2012 Reviewed Reviewer Report - Shigeaki Kato
9 Jan 2013 Author responded Author comments - Rosanna Weksberg
Resubmission - Version 5
9 Jan 2013 Submitted Manuscript version 5
Publishing
14 Jan 2013 Editorially accepted
28 Jan 2013 Article published 10.1186/1755-8794-6-1

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article and author comments to reviewers are available by contacting info@biomedcentral.com. All previous versions of the manuscript and all author responses to the reviewers are also available.

You can find further information about the peer review system here.

Authors’ Affiliations

(1)
Genetics and Genome Biology Program, Hospital for Sick Children
(2)
Division of Clinical and Metabolic Genetics, Hospital for Sick Children
(3)
Centre of Reproduction, Growth & Development, Department of Pediatrics & Adolescent Medicine, The University of Hong Kong
(4)
Program in Molecular Structure and Function, Hospital for Sick Children
(5)
J.C. Self Research Institute, Greenwood Genetic Center
(6)
Department of Pediatric Laboratory Medicine, Hospital for Sick Children
(7)
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health
(8)
Division of Endocrinology, Department of Pediatrics, Hospital for Sick Children
(9)
Department of Pediatrics, University of Toronto
(10)
Department of Molecular and Medical Genetics, University of Toronto
(11)
The Centre for Applied Genomics, Hospital for Sick Children

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