Figure 3

Expression of the ALDH1A3 gene in pancreatic cell lines and tissue samples. Expression levels for ALDH1A3 were determined by RT-qPCR in (A) normal derived pancreatic tissue samples (N-1 though N-10) and tumor derived pancreatic tissue samples (T1 through T10), as well as (B) in pancreatic normal (n=1) and tumor (n=12) derived cell lines. Expression levels were normalized to the geometric mean of B2M and PPIA and are shown in arbitrary units (A.U.). Chromosomal gain of the ALDH1A3 gene region is indicated below panel (B) as G: copy number gain, N: no gain. Copy number alterations were not assessed for cell lines marked with “–“. (C) ALDH1A3 expression levels were assessed in additional pancreatic cancer cell lines (n=39) by RT-qPCR.