Curation-free biomodules mechanisms in prostate cancer predict recurrent disease

BMC Medical Genomics

Table 1 Prostate cancer datasets analyzed

Author	Phenotype	Samples Analyzed	Usage	Source
[11]	Normal vs Tumor	Authors examined 61 microdissected prostate cancer specimens along with 63 normal prostate tissues samples adjacent to tumor of patients.	Feature Selection	GDS2547
[12]	Normal vs Tumor	Authors examined 33 African-American and 36 European-American patients with prostate cancer. Also profiled 18 non-tumor prostate tissues from 7 African-American and 11 European-American patients.	Feature Selection	GSE6956
[13]	Normal vs Tumor	Comprehensive set from Memorial Sloan Ketting tumor bank in prostate tumors from 53 patients with primary or metastatic prostate cancer and 29 normal controls.	Feature Selection	GSE21032
[14]	Disease free interval survival	79 tumors were obtained from the Memorial Sloan Kettering tumor bank. The authors identified three signatures of early recurrence (within one year).	Validation Set	From author

The first three datasets are used for mechanism feature selection reported in Table 2 and Figure 1. The fourth dataset serves as independent validation as depicted in Figure 3.

ISSN: 1755-8794