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Table 2 Enriched gene ontology categories in genes with multiple TSRs

From: The global landscape of intron retentions in lung adenocarcinoma

Categorya

Term

Correctedb

Classc

hsa05322

Systemic lupus erythematosus

4.99E-08

KEGG

GO:0005583

Fibrillar collagen

0.00163

GO:CC

hsa03010

Ribosome

1.74E-03

KEGG

GO:0005201

Extracellular matrix structural constitu…

0.006651

GO:MF

GO:0007411

Axon guidance

0.009976

GO:BP

GO:0043062

Extracellular structure organization

0.009976

GO:BP

GO:0030199

Collagen fibril organization

0.009976

GO:BP

hsa00970

Aminoacyl-tRNA biosynthesis

1.03E-02

KEGG

hsa04370

VEGF signaling pathway

1.03E-02

KEGG

GO:0048407

Platelet-derived growth factor binding

0.011402

GO:MF

GO:0044420

Extracellular matrix part

0.015466

GO:CC

GO:0005581

Collagen

0.015466

GO:CC

GO:0030198

Extracellular matrix organization

0.020783

GO:BP

GO:0006935

Chemotaxis

0.022168

GO:BP

GO:0042330

Taxis

0.022168

GO:BP

GO:0031256

Leading edge membrane

0.028215

GO:CC

hsa04510

Focal adhesion

3.64E-02

KEGG

GO:0005578

Proteinaceous extracellular matrix

0.047652

GO:CC

  1. aCategories with more than 1000 genes were removed.
  2. bFisher’s exact test after Benjamini-Hochberg correction.
  3. cGO: gene ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; BP: biological process; MF: molecular function; CC: cellular component.