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Table 2 Recurrent mutations detected in both exome- and RNA-seq

From: Conserved recurrent gene mutations correlate with pathway deregulation and clinical outcomes of lung adenocarcinoma in never-smokers

Gene

Number of samples with mutation (from 27)

Frequency of mutation

EGFR

4

14.8%

KRAS

3

11.1%

TP53

3

11.1%

RPS6KB2

3

11.1%

PTPN13

2

7.4%

SP1

2

7.4%

SPTAN1

2

7.4%

MYOF

2

7.4%

ATXN2

2

7.4%

DHX9

2

7.4%

  1. Genes with recurrent mutations. 15 out of 27 samples (55.6%) had one or more mutations in 10 genes with recurrent mutations.