Figure 4From: Integrated differential transcriptome maps of Acute Megakaryoblastic Leukemia (AMKL) in children with or without Down Syndrome (DS) Biological model of the transcriptome depicting progressive changes from MK to TMD then to DS AMKL. Downward pointing arrow indicates the repression of genes involved in MK differentiation; upward pointing arrow indicates the over-expression of potential molecular markers of progression to AMKL. Value: mean gene expression value normalized across all the pool samples. §Observed both in DS and non-DS AMKL.Back to article page