Module (Module size) | Â | S I | Hub gene* (r, P) | Module genes # associated with S I (r) | AIRg | HOMA-IR | Matsuda Index | BMI | % Fat mass | TG | HDL | GO Gene Category Overlap, P, Corrected-P |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Tan (268) | r | 0.463 | ANG (0.35, 0.0004) | PFKFB3(0.53), LOC647276(0.52) | −0.471 | −0.572 | 0.525 | −0.677 | −0.523 | −0.42 | 0.378 | Enoyl-CoA hydratase activity |
p | 1.02E-04 | 6.92E-05 | 0.00243 | 1.33E-09 | 6.7E-13 | 4.1E-08 | 0.045 | 0.000132 | 3, 0.000046,NS | |||
Thistle (88) | r | −0.531 | ITGB5 (−0.41, <0.00001) | PLAC9(−0.46), ITGB5(−0.44) | 0.307 | 0.493 | −0.459 | 0.662 | 0.522 | 0.467 | −0.44 | Cellular defense response |
p | 2.9E-06 | 0.00323 | 0.022 | 8.70E-07 | 1.7E-12 | 5E-08 | 0.003 | 0.0000328 | 6, 0.000039,NS | |||
Yellow (1027) | r | −0.426 | TYROBP (−0.37, 0.0002) | KIAA1598(−0.53), ITGAV(−0.52) | 0.286 | 0.384 | −0.364 | 0.607 | 0.414 | 0.44 | −0.414 | Inflammatory response |
p | 4.95E-04 | 0.0493 | 0.113 | 0.000674 | 4E-09 | 3.72E-04 | 0.047 | 0.00045 | 93, 3.2E-30,1.7E-26 | |||
Hot pink (89) | r | −0.438 | PTPN11 (−0.37, 0.0002) | TMEM54(−0.44), SLC46A3(−0.4) | 0.247 | 0.514 | −0.444 | 0.593 | 0.436 | 0.421 | −0.231 | Substrate-bound cell migration |
p | 3.90E-04 | 0.00786 | 0.0353 | 7.82E-06 | 9.1E-08 | 6E-06 | 0.081 | 0.00741 | 4, 0.00025,NS | |||
Peru (167) | r | −0.423 | NQO1 (−0.43, <0.00001) | GNG2(−0.53), UCHL1(−0.5) | 0.198 | 0.475 | −0.405 | 0.683 | 0.511 | 0.364 | −0.262 | Steroid metabolism |
p | 6.02E-04 | 0.0341 | 0.055 | 7.13E-05 | 1.5E-12 | 2E-08 | 0.038 | 0.00662 | 10, 0.0000059,0.031 | |||
Pink (359) | r | 0.411 | SDHB (0.27, 0.0073) | AZGP1(0.5), CKB(0.49) | −0.306 | −0.353 | 0.344 | −0.491 | −0.362 | −0.36 | 0.418 | Mitochondrion |
p | 3.53E-04 | 0.024 | 0.161 | 0.000372 | 9.7E-07 | 0.0002 | 0.032 | 0.00133 | 87, 3.6E-59,1.9E-55 | |||
Forest green (118) | r | −0.321 | LOC728973 (0.30, 0.0022) | SNCG(−0.35), CES2(−0.35) | 0.272 | 0.418 | −0.42 | 0.455 | 0.29 | 0.311 | −0.182 | Telomerase holoenzyme complex |
p | 0.0691 | 0.0535 | 0.198 | 0.00476 | 0.00222 | 0.0104 | 0.434 | 0.102 | 2, 0.00024,NS | |||
Light yellow (186) | r | 0.413 | DCI (0.39, <0.00001) | ARHGEF16(0.44), HADH(0.43) | −0.306 | −0.336 | 0.323 | −0.409 | −0.269 | −0.38 | 0.344 | Mitochondrion |
p | 7.3E-06 | 0.00765 | 0.0767 | 2.68E-06 | 1.6E-05 | 0.00163 | 0.038 | 0.00238 | 27, 1.1E-11, 5.8E-08 |