Blood-based identification of non-responders to anti-TNF therapy in rheumatoid arthritis

BMC Medical Genomics

Table 2 Classifier linear model

Patients with classifier scores above 5.96 are predicted non-responders and thus potential candidates for alternative biologic therapy. Patients with classifier scores below this threshold were not predicted as non-responders and are assumed to be a mix of responders and non-responders. The number of genes supporting each mechanism varies based on the microarray platform used in each of the four training data sets. Note that the magnitudes of the coefficients do not necessarily indicate relative importance of the mechanisms for predicting non-response

ISSN: 1755-8794