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Table 3 Distribution of changes in perceived risk from baseline to follow-up, stratified by cancer, genetic result, and follow-up time

From: The impact of direct-to-consumer personal genomic testing on perceived risk of breast, prostate, colorectal, and lung cancer: findings from the PGen study

 

Breast

Prostate

Colorectal

Lung

Genetic risk result

Average

Elevated

Average

Elevated

Average

Elevated

Average

Elevated

2-week follow-up

Frequency, n (%)

514 (89.2)

62 (10.8)

278 (78.5)

76 (21.5)

728 (75.1)

241 (24.9)

781 (80.8)

185 (19.2)

Unit change in perceived risk (%)

 −4

0.0

0.0

0.0

0.0

0.1

0.0

0.1

0.0

 −3

0.6

0.0

1.4

0.0

0.7

0.4

0.5

0.0

 −2

6.8

6.5

5.0

1.3

3.6

0.8

2.7

1.6

 −1

23.7

6.5

26.6

14.5

22.7

11.6

19.1

11.4

 0

51.6

37.1

51.1

25.0

50.0

38.2

47.0

37.3

 + 1

14.0

35.5

14.0

35.5

19.2

35.7

24.2

31.9

 + 2

3.3

14.5

1.4

14.5

3.7

9.5

5.9

12.4

 + 3

0.0

6.5

0.4

7.9

0.0

3.7

0.5

5.4

 + 4

0.0

0.0

0.0

1.3

0.0

0.0

0.0

0.0

6-month follow-up

        

Frequency, n (%)

511 (90.4)

54 (9.6)

266 (77.6)

77 (22.4)

717 (75.7)

230 (24.3)

773 (81.8)

172 (18.2)

Unit change in perceived risk (%)

 −4

0.0

0.0

0.0

0.0

0.0

0.0

0.1

0.0

 −3

0.6

1.9

0.8

0.0

0.1

0.0

0.7

0.0

 −2

6.7

0.0

4.9

5.2

4.6

1.7

2.7

1.7

 −1

23.1

18.5

26.3

10.4

21.5

15.7

18.4

12.8

 0

50.9

33.3

51.5

32.5

52.4

40.9

48.0

41.3

 +1

13.9

27.8

14.7

33.8

16.9

30.0

22.9

27.9

 +2

4.5

13.0

1.9

10.4

4.2

9.6

6.3

10.5

 +3

0.4

1.9

0.0

5.2

0.1

2.2

0.8

5.8

 +4

0.0

3.7

0.0

2.6

0.1

0.0

0.1

0.0