Demographic characteristics | Euploid (n = 96) | T21 (n = 5) | P value | Total (n = 101) |
---|---|---|---|---|
Maternal age, years, mean ± SD | 35.55 ± 3.63 | 33.40 ± 3.64 |  | 35.45 ± 3.64 |
≥35 years (%) | 59 (61.46) | 1(20.00) |  | 60 (59.41) |
NIPT during gestational week 11–13 (%) | 67 (69.79) | 3 (60.0) |  | 70 (69.31) |
NIPT during gestational week 14–18 (%) | 29 (30.21) | 2 (40.0) |  | 31 (30.69) |
PGM, z-score of chr21 (min, max) | −3.46, 2.07 | 5.50, 9.43 | <0.0001†| −3.46, 9.43 |
Proton, z-score of chr21 (min, max) | −2.32, 2.10 | 6.20, 8.86 | <0.0001†| −2.32, 8.96 |