Table 6 Communities membership and scores
Communities | Genes | Average ConsenScore i | Average Rank | Average Degree | N Pathogenic | N Pathways |
|---|---|---|---|---|---|---|
2 | TGFB1, SRC,IGF1,IL6, INS, LEP, NOS3, AKT1, ICAM1, MMP2, STAT3, VEGFA, EDN1, MMP9 | 0,995 | 89,07 | 55.21 | 5 | 8 |
6 | TGFB1, TGFB3, EGF, VWF, IGF1, F2, KNG1, PPBP, SERPINE1, TIMP1, FN1, PLG, VEGFA, IGF2, CLU, F13A1, FIGF, MMRN1, PF4, SPARC, VEGFB, VEGFC, F5, TGFB2, PROS1 | 0,991 | 171,28 | 38.24 | 5 | 7 |
9 | TGFB1, IL6, NFKB1, TP53, AKT1, MMP2, BCL2, MYC, MMP9 | 0,989 | 194,56 | 52.33 | 2 | 6 |
1 | IL6, IL2, STAT3, IFNG, STAT5A, JAK2, JAK1, SOCS3, STAT1, IL6ST | 0,989 | 210,2 | 39.60 | 1 | 4 |
8 | MAPK1, MAPK3, NFKB1, IL2, STAT3, RELA, CSF2, JAK2, MYC | 0,989 | 210,67 | 44.89 | 0 | 14 |
5 | AGT, AGTR1, BDKRB2, EDNRA, F2R, F2RL2, F2RL3, GNA11, GNAQ, KNG1, OXTR, PIK3R1, PLCG1, PROK1, RGS2, TAC1, TAC3, TACR1, TACR3, UTS2, EDN1, EDNRB, HTR2A, KISS1, TACR2, TBXA2R | 0,987 | 231,04 | 33.88 | 4 | 7 |
3 | ADM, CRH, POMC, ADORA2B, PTGIR, TSHR, ADRB2, ADRB3, CALCA, CRHR2, GNAS, FSHR | 0,987 | 243,92 | 16.50 | 1 | 3 |
4 | POMC, CCR5, AGT, APLN, BDKRB2, C3, CCL5, CCR2, CXCL10, CXCR1, CXCR2, DRD4, IL8, KNG1, NPY, PPBP, CXCL1 | 0,985 | 273,25 | 28.75 | 1 | 5 |
7 | COL18A1, COL1A1, COL1A2, COL3A1, COL4A5, COL2A1, COL4A1, COL4A2, COL4A6, COL5A1, COL4A3, COL4A4 | 0,983 | 304,5 | 15.58 | 0 | 2 |