Table 3 Distribution profile and frequency of chromosomal abnormalities in different maternal and gestational ages
From: Experience of copy number variation sequencing applied in spontaneous abortion
| Â | CNVs (n, %) | Monosomy X (n, %) | Autosomal trisomy (n, %) |
|---|---|---|---|
Gestational age | |||
 < 13 weeks (N = 597) | 91 (15.2) | 35 (5.9) | 204 (34.2) |
 ≥ 13 weeks (N = 53) | 9 (17.0) | 4 (7.5) | 10 (18.9) |
 X2 | 0.113 | 0.245 | 5.162 |
 P | 0.737 | 0.621 | 0.023 |
Maternal age | |||
 ≤ 29 (N = 255) | 45 (17.6) | 20 (7.8) | 59 (23.1) |
 30–34 (N = 234) | 43 (18.4) | 12 (5.1) | 75 (32.1) |
 35–39 (N = 125) | 8 (6.4) | 6 (4.8) | 58 (46.4) |
 ≥ 40 (N = 36) | 4 (11.1) | 1 (2.8) | 22 (61.1) |
 X2 | 10.868 | 2.833 | 34.371 |
 P | 0.012 | 0.418 | 0.000 |