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Table 2 Demographic and biochemical characteristics of all studied groups

From: Vitamin D receptor rs3782905 and vitamin D binding protein rs7041 polymorphisms are associated with hepatocellular carcinoma susceptibility in cirrhotic HCV patients

Parameter

Normal Controls (N = 100)

Cirrhotic Patients (N = 100)

HCC patients (N = 99)

P value N = 100

Demographic Data

Age (year)(Median IQR)

33 (26–45)

50 (42.25–58.75)a,b

55 (47–60)a

p < 0.001

Gender: M/F

40/60

39/61

46/53

NS

Smoking status (n %)

   

NS

 Non-smokers

56 (56%)

60 (60%)

63 (63.6%)

 

 Smokers

44 (44%)

40 (40%)

36 (36.4%)

 

Laboratory Data (median IQR)

 ALT (IU/L)

18 (12–23)

82 (68.5–93.5)a,b

11 (101–118)a

p < 0.001

 AST(IU/L)

19 (14–25)

70 (59–82.25)a,b

104 (96–110)a

p < 0.001

 ALB (g/L)

3.8 (3.6–4.07)

3.2 (3.1–3.3)a,b

2.7 (2.6–2.9)a

p < 0.001

 Creatinine (mg/dL)

0.8 (0.70–1.0)

1.6 (1.4–1.7)a,b

2.1 (2–2.2)a

p < 0.001

 T.Billirubin (mg/dL)

0.56 (0.50–0.70)

1.6 (1.4–1.7)a,b

2.6 (2.4–2.8)a

p < 0.001

 D. Billirubin (mg/dL)

0.12 (0.07–0.16)

0.69 (0.55–0.79)a,b

1.2 (1.1–1.3)a

p < 0.001

 AFP (ng/mL)

17 (12.25–20.75)

64.5 (46.25–74.75)a,b

715 (495–822)a

p < 0.001

  1. aSignificante from normal controls
  2. bSignificance from HCC patients