Table 4 Comparison of all groups under study's VDR and DBP gene polymorphisms' association haplotypes
Haplotypes | Normal Control (N = 100) | Cirrhotic patients (N = 100) | HCC patients (N = 99) | Cirrhotic patients vs normal controls | HCC patients vs normal controls | HCC patients vs Cirrhotic patients | |||
|---|---|---|---|---|---|---|---|---|---|
| Â | OR (95% CI) | P value | OR (95% CI) | P Value | OR (95% CI) | P Value | |||
CTG | 24.89% | 9.74% | 10.2% | 0.312 (0.136–0.731) | p < 0.01 | 0.351 (0.157–0.780) | p < 0.01 | 1.123 (0.435–2.896) | NS |
CTC | 17.4% | 19.39% | 14.4% | 1.145 (0.555–2.36) | NS | 2.02 (0.88–4.62) | NS | 1.06 (0.51–2.21) | NS |
CGG | 11.54% | 10.37% | 19.63% | 0.898 (0.363–2.223) | NS | 2.85 (1.18–6.89) | p < 0.05 | 2.16 (1.02–4.55) | p < 0.05 |
TTG | 20.06% | 5.35% | 5.37% | 0.210 (0.075–0.585) | p < 0.01 | 0.73 (0.25–2.15) | NS | 3.60 (1.39–9.28) | p < 0.001 |
CGC | 4.18% | 27.49% | 18.33% | 8.9 (2.98–26.527) | p < 0.001 | 5.34 (2.08–13.74) | p < 0.001 | 1.59 (0.69–3.67) | NS |
TGC | 2.77% | 6.1% | 16.43% | 3.129 (0.615–15.89) | NS | 14.74 (3.38–64.26) | p < 0.001 | 1.57 (0.71–3.45) | NS |
TGG | 9.0% | 8.54% | 10.77% | 0.879 (0.324–2.385) | NS | 1.48 (0.60–3.64) | NS | 0.51 (0.18–1.43) | NS |
TTC | 10.16% | 13.02% | 4.81% | 1.345 (0.560–3.230) | NS | 0.52 (0.13–2.16) | NS | 1.33 (0.40–4.41) | NS |