Table 6 Gender and SNPs of VDR and DBP geneassociation analyses in cirrhotic and HCC patients
| Â | Male | Â | Female | Â | ||
|---|---|---|---|---|---|---|
SNPs | Cirrhosis N = 39 (N %) | HCC N = 46 (N %) | P value OR (95% CI) | Cirrhosis N = 61 (N %) | HCC N = 53 (N %) | P value OR(95% CI) |
VDR(rs2228570) | ||||||
 CC | 22 (56.5) | 21 (45.7) | NS 0.65 (0.28–1.53) | 32 (52.5) | 25 (47.1) | NS 0.81(0.39–1.69) |
 CT | 10 (25.6) | 14 (30.4) | NS 1.27 (0.49–3.29) | 16 (26.2) | 18 (34) | NS 1.45 (0.65–3.24) |
 TT | 7 (17.9) | 11 (23.9) | NS 1.44 (0.50–4.16) | 13 (21.3) | 10 (18.9) | NS 0.86 (0.34–2.16) |
VDR(rs3782905) | ||||||
 GG | 7 (17.9) | 9 (19.6) | NS 1.11 (0.37–3.33) | 12 (19.7) | 14 (26.4) | NS 1.47 (0.613.53) |
 GC | 11 (28.3) | 23 (50) | p < 0.05 2.56 (1.03–6.30) | 19 (31.1) | 22 (41.5) | NS 1.57 (0.733.39) |
 CC | 21 (53.8) | 14 (30.4) | p < 0.05 0.38 (0.15–0.91) | 30 (49.2) | 17 (32.1) | NS 0.49 (0.231.05) |
DBP(rs7041) | ||||||
 TT | 13 (33.4) | 11 (23.9) | NS 0.63 (0.24–1.63) | 10 (16.4) | 9 (17) | NS 1.04 (0.39–2.80) |
 TG | 16 (41) | 18 (39.1) | NS 0.92 (0.38–2.21) | 33 (54.1) | 11 (20.8) | p < 0.001 0.22 (0.10–0.51) |
 GG | 10 (25.6) | 17 (37) | NS 1.70 (0.67–4.33) | 18 (29.5) | 33 (62.2) | p < 0.01 3.94 (1.80–8.61) |