Causal associations between liver traits and Colorectal cancer: a Mendelian randomization study

BMC Medical Genomics

Table 1 Heterogeneity and pleiotropy of individual single nucleotide polymorphisms for Mendelian randomization

Exposure	Heterogeneity		Pleiotropy
Exposure	Cochran’s Q statistic (IVW)	P value	MR-Egger intercept	P value
Liver iron content	3.0	0.70	0.0021	0.93
Percent liver fat	11	0.30	0.0060	0.75
Liver alanine transaminase levels	2.7 × 10²	0.0050	-0.0014	0.88
Liver volume	9.5	0.40	0.032	0.21

ISSN: 1755-8794