Table 3 Genotypic frequencies and association analysis of SNPs among psoriasis patients
From: Mutations in PGRN gene associated with the risk of psoriasis in Pakistan: a case control study
SNP | χ2 | Odds Ratio (95% CI) | p value | Genotype | Patients [n (%)] | Controls [n (%)] |
|---|---|---|---|---|---|---|
rs25646 | 82.61 | 6.217 (3.34–11.57) | p < 0.001 | TT TC CC | 45 (26.32) 30 (17.54) 96 (56.14) | 109 (63.74) 44 (25.73) 18 (10.53) |
rs850713 | 88.21 | 6.668 (3.51–12.66) | p < 0.001 | GG GA AA | 50 (29.24) 33 (19.30) 88 (51.46) | 136 (79.53) 6 (3.51) 29 (16.96) |
805 A/G | 25.18 | 2.875 (1.20–6.88) | p < 0.001 | AA AG GG | 105 (61.40) 63 (36.84) 3 (1.75) | 146 (85.38) 24 (14.04) 1 (0.58) |