Fig. 7
Volcano plots and heatmaps of DEGs (left) and DMRs (right) of patients with variants and without variants in TCGA-STAD. The VX means a patient who does not have variants (n = 364 in DEGs, n = 384 in DMRs) and the VY (n = 9 in DEGs, n = 9 in DMRs) is the opposite. In the volcano plot, red dots indicate DEGs and DMRs with increased expression or methylation levels in the variants containing (VY) group. The dashed blue line represents where P < 10−10 for DEGs and P < 10−12 for DMRs. Patients without variants are denoted as VX and patients with variants are denoted as VY. The colored dots were provided as total five DEGs and five DMRs, which were listed as two heatmaps. In heatmap, vital status, gender, and variants are indicated as column annotation bars Two row annotation bars indicate P-value and fold change between two groups