Table 3 Generalized estimating equation analysis for outcomes of PGT-A
Variable | AZFc microdeletion | Control | Adjusted OR(95% CI) | P value |
|---|---|---|---|---|
No. of cycles | 58 | 545 | - | - |
No. of patients | 53 | 460 | - | - |
No. of blastocysts biopsied (%) | 294 | 2833 | - | - |
No. of euploid embryos (%) | 157 (53.4) | 1650 (58.2) | 0.676 (0.502–0.912) | 0.010 |
No. of aneuploid embryos (%) | 97 (33.0) | 772 (27.3) | 1.654 (1.197–2.286) | 0.002 |
No. of entire chromosome aneuploid embryos (%) | 61 (20.8) | 481 (17.0) | 1.807 (1.227–2.660) | 0.003 |
No. of segmental aneuploid embryos (%) | 32 (10.9) | 225 (7.9) | 1.235 (0.745–2.050) | 0.413 |
No. of complex aneuploid embryos (%) | 4 (1.4) | 66 (2.3) | 0.896 (0.309–2.598) | 0.840 |
No. of mosaic embryos (%) | 28 (9.5) | 305 (10.8) | 0.981 (0.579–1.661) | 0.942 |
No. of uninformative embryos (%) | 12 (4.1) | 106 (3.7) | 0.881 (0.421–1.841) | 0.736 |
No. of embryos with monosomy X (%) | 4 (1.4) | 24 (0.8) | 1.635 (0.437–6.127) | 0.465 |