Table 1 Mendelian randomization estimates lipid profiles and insomnia
Traits | Methods | Nsnp | OR(95%CI) | P-Value |
|---|---|---|---|---|
TG | MR-Egger regression | 37 | 1.1505(0.7552, 1.7528) | 0.518 |
Weighted median | 1.1165(0.8173, 1.5252) | 0.489 | ||
IVW(fixed effect) | 1.1114(0.8880, 1.3910) | 0.356 | ||
ApoA-1 | MR-Egger regression | 10 | 0.8484(0.4784, 1.5035) | 0.589 |
Weighted median | 0.7945(0.6063, 1.0410) | 0.095 | ||
IVW(fixed effect) | 0.7546(0.6075, 0.9372) | 0.011 | ||
ApoB | MR-Egger regression | 18 | 1.0743(0.7930, 1.4554) | 0.650 |
Weighted median | 1.0725(0.8542, 1.3465) | 0.547 | ||
IVW(fixed effect) | 1.0911(0.9231, 1.2896) | 0.307 | ||
LPA | MR-Egger regression | 40 | 0.7183(0.5626, 0.9170) | 0.012 |
Weighted median | 0.8605(0.7033, 1.0528) | 0.144 | ||
IVW(fixed effect) | 0.8392(0.7202, 0.9778) | 0.025 |