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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Novel autosomal dominant TMC1 variants linked to hearing loss: insight into protein-lipid interactions

Fig. 2

Three-dimensional modeling and structural analysis of p.Phe419Ser TMC1 variants. Three-dimensional model structure of TMC1 wild type and p.Phe419Ser mutant. Transmembrane domain 4 (black), Phe419 residue (orange), p.Phe419Ser mutagenesis (yellow), and stick models of phosphatidylcholine (gray). Compromised protein-lipid interaction of p.Phe419Ser mutant in membranous condition

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BMC Medical Genomics

ISSN: 1755-8794

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