Table 2 Frequency of NAT2 alleles (N = 79)
NAT2 allele | Mutation site | Amino acid change | Reference ID | Acetylation status | Number of participants (N) | Frequency (95% CI) |
|---|---|---|---|---|---|---|
NAT2*4 | – | WILD | – | Rapid | 29 | 0.367 (0.269–0.477) |
NAT2*13 | 282C > T | Tyr94Tyr | rs1041983 | Rapid | 23 | 0.291 (0.203–0.399) |
NAT2*5 | 341 T > C | Ile114Thr | rs1801280 | Slow | 14 | 0.177 (0.109–0.276) |
NAT2*12 | 803A > G | Arg268Lys | rs1208 | Rapid | 5 | 0.063 (0.027–0.140) |
NAT2*6 | 590G > A | Arg197Gln | rs1799930 | Slow | 5 | 0.063 (0.027–0.140) |
NAT2*11 | 481C > T | Leu161Leu | rs1799929 | Rapid | 3 | 0.038 (0.013–0.106) |