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Table 5 Comparison of the Predicted phenotype by sociodemographic characteristics

From: Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity

Variable

Frequency

Predicted phenotype

p-value

OR (95% CI)a

(N = 79)

Rapid

(N = 60)

Slow (N = 19)

Gender (n, %)

     

 Female

51 (65%)

43 (72%)

8 (42%)

–

–

 Male

28 (35%)

17 (28%)

11 (58%)

0.022

3.48 (1.21–10.48)

Age group (n, %)

     

 < 30

16 (20%)

13 (23%)

3 (16%)

–

–

 30–39

26 (33%)

18 (30%)

8 (42%)

0.394

1.93 (0.46–10.10)

  ≥ 40

37 (47%)

29 (48%)

8 (42%)

0.813

1.20 (0.29–6.12)

Ethnicity (n, %)

     

 Eastern Bantu

50 (63%)

40 (67%)

10 (53%)

–

–

 Western Bantu

14 (18%)

8 (13%)

6 (32%)

0.089

3.00 (0.83–10.76)

   Nilotic

11 (14%)

8 (13%)

3 (16%)

0.596

1.50 (0.29–6.33)

   Cushite

4 (5%)

4 (7%)

0 (0%)

0.993

–

HIV status (n, %)

     

 Negative

38 (48%)

28 (47%)

10 (53%)

–

–

 Positive

41 (52%)

32 (53%)

9 (47%)

0.651

0.79 (0.28–2.22)

  1. a OR Odds ratio, CI Confidence Interval, Logistic regression analysis