Table 2 Frequency of gene polymorphisms in two groups
Gene | SNP | Genotype | High-degree CAC (n = 173) | Low-degree CAC (n = 699) | P value |
|---|---|---|---|---|---|
NPC1L1 | rs11763759 | TT | 153 (88.4%) | 622 (89.1%) | 0.587 |
CT | 20 (11.6%) | 71 (10.2%) | |||
CC | 0 (0.0%) | 5 (0.7%) | |||
| Â | rs4720470 | CC | 75 (43.6%) | 340 (48.6%) | 0.402 |
| Â | CT | 78 (45.3%) | 278 (39.8%) | ||
| Â | TT | 19 (11.0%) | 81 (11.6%) | ||
| Â | rs2072183 | GG | 64 (37.0%) | 278 (39.9%) | 0.577 |
| Â | CG | 81 (46.8%) | 326 (46.8%) | ||
| Â | CC | 28 (16.2%) | 93 (13.3%) | ||
| Â | rs2073547 | AA | 64 (37.0%) | 276 (39.5%) | 0.668 |
| Â | GA | 81 (46.8%) | 327 (46.8%) | ||
| Â | GG | 28 (16.2%) | 96 (13.7%) | ||
HMGCR | rs12916 | TT | 40 (23.3%) | 172 (24.7%) | 0.302 |
TC | 89 (51.7%) | 317 (45.5%) | |||
CC | 43 (25.0%) | 208 (29.8%) | |||
| Â | rs2303151 | CC | 118 (68.2%) | 440 (62.9%) | 0.424 |
| Â | CT | 48 (27.7%) | 229 (32.8%) | ||
| Â | TT | 7 (4.0%) | 30 (4.3%) | ||
| Â | rs4629571 | AA | 149 (86.1%) | 570 (81.5%) | 0.387 |
| Â | AG | 22 (12.7%) | 120 (17.2%) | ||
| Â | GG | 2 (1.2%) | 9 (1.3%) |