Fig. 2

Classification of HCC subtypes and related clinical features analysis. (A) The CDF distribution diagram shows value of CDF under different k value, the red line with k = 2 is most smoothest (Left); the relative change in area under CDF curve is shown on the right and the largest difference is between k = 2 and k = 3. (B) The diagram illustrating the consistency matrix when k = 2. (C) Heatmap of clinical traits (TNM, stage, grade, gender, age) of two subtypes (*p < 0.05, **p < 0.01, ***p < 0.001). (D) Comparison of the proportion between two subtypes regarding gender, grade, stage, and T staging. (E) Kaplan-Meier survival analysis of two subtypes. (F) Heatmap of two subtypes from KEGG gene sets and hallmark gene sets of the MsigD