HLA/SNPs allele | Tolerant control (n = 101) n (%) | cADRs (n = 57) n (%) | SJS/TEN (n = 25) n (%) | DRESS (n = 24) n (%) | MPE (n = 8) n (%) |
---|---|---|---|---|---|
HLA-B*5801 | 4 (3.9) | 49 (85.9) | 24 (96.0) | 19 (79.2) | 6 (75.0) |
BAT1 rs2734583, A > G | 7 (6.9) | 44 (77.2) | 22 (88.0) | 19 (79.2) | 3 (37.5) |
BAT3 rs3117583, A > G | 16 (15.8) | 38 (66.7) | 20 (80.0) | 14 (58.3) | 4 (50.0) |
CCHCR1 rs130077, G > A | 7 (6.9) | 48 (84.2) | 24 (96.0) | 19 (79.1) | 5 (62.5) |
CCHCR1 rs9263745, G > A | 7 (6.9) | 49 (85.9) | 24 (96.0) | 19 (79.1) | 6 (75.0) |
CCHCR1 rs9263785, T > G | 7 (6.9) | 48 (84.2) | 24 (96.0) | 19 (79.1) | 5 (62.5) |
HCP5 rs3099844, C > A | 8 (7.9) | 45 (78.9) | 22 (88.0) | 20 (83.3) | 4 (50.0) |
HCP5 rs3131643, G > A | 15 (14.9) | 46 (80.7) | 22 (88.0) | 20 (83.3) | 3 (37.5) |
HLAC rs4084090, A > G | 11 (10.9) | 49 (85.9) | 24 (96.0) | 20 (83.3) | 5 (62.5) |
MSH5 rs1150793, A > G | 18 (17.8) | 38 (66.7) | 19 (76.0) | 14 (58.3) | 4 (50.0) |
POLR2LP rs9263733, C > T | 5 (4.9) | 48 (84.2) | 24 (96.0) | 19 (79.2) | 5 (62.5) |
POU5F1 rs9263796, C > T | 7 (6.9) | 48 (84.2) | 24 (96.0) | 19 (79.1) | 5 (62.5) |
PSORS1C1 rs2233945, C > A | 7 (6.9) | 47 (82.5) | 24 (96.0) | 18 (75.0) | 5 (62.5) |
PSORS1C1 rs9263726, G > A | 7 (6.9) | 48 (84.2) | 24 (96.0) | 19 (79.2) | 5 (62.5) |
TCF19 rs1044870, C > T | 0 (0) | 14 (24.6) | 2 (8.0) | 8 (33.3) | 4 (50.0) |
TCF19 rs9263794, A > G | 12 (11.9) | 49 (85.9) | 24 (96.0) | 20 (83.3) | 5 (62.5) |