Skip to main content

Table 4 The fitted linear mixed effect models for each biomarker expression within Gleason grade 3+3 tumors, where zone of origin (TZ vs. PZ) was fitted as a fixed effect and patient as a random effect.

From: Biomarker expression patterns that correlate with high grade features in treatment naive, organ-confined prostate cancer

Marker Variable Coefficient SE P-value
Bax Intercept 2.73 0.18 -
  TZ (vs. PZ) -2.27 0.32 < 0.0001
Bcl-XL Intercept 3.58 0.15 -
  TZ (vs. PZ) -0.25 0.15 0.12
Bin1 Intercept 2.13 0.25 -
  TZ (vs. PZ) -1.47 0.44 0.005
FAS Intercept 0.27 0.22 -
  TZ (vs. PZ) -0.20 0.39 0.61
MDM2 Intercept 2.81 0.60 -
  TZ (vs. PZ) -2.81 1.04 0.02
P21 Intercept 2.67 0.28 -
  TZ (vs. PZ) -2.13 0.49 0.0008
P65 Intercept 1.67 0.37 -
  TZ (vs. PZ) -1.67 0.63 0.02