Table 3 Genes downregulated in palmar fascia fibroblasts obtained from Dupuytren's Contracture using Illumina™ Platform.
Gene ID | Gene Name | Fold Change | |
|---|---|---|---|
1. | NM_005807 | Homo sapiens proteoglycan 4 (PRG4), mRNA. | 0.08 |
2. | NM_020299 | Homo sapiens aldo-keto reductase family 1, member B10 aldose reductase) (AKR1B10), mRNA. | 0.15 |
3. | NM_145176 | Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 12 (SLC2A12), mRNA. | 0.18 |
4. | NM_001831 | clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1 | 0.21 |
5. | NM_012168 | F-box protein 2 (FBXO2), mRNA | 0.21 |
6. | NM_139125 | Homo sapiens mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1), transcript variant 2, mRNA. | 0.22 |
7. | NM_000691 | Homo sapiens aldehyde dehydrogenase 3 family, memberA1 (ALDH3A1), mRNA | 0.22 |
8. | NM_178127 | Homo sapiens angiopoietin-like 5 (ANGPTL5), mRNA | 0.23 |
9. | NM_004000 | chitinase-3-like 2 (CHI3L2) | 0.22 |
10. | NM_005410 | Homo sapiens selenoprotein P, plasma, 1 (SEPP1), mRNA | 0.23 |
11. | NM_001996 | Homo sapiens fibulin 1 (FBLN1), transcript variant C, mRNA | 0.24 |
12. | NM_015714 | Homo sapiens G0/G1switch 2 (G0S2), mRNA | 0.24 |
13. | NM_021146 | angiopoietin-like factor (CDT6) | 0.24 |
14. | NM_006486 | Homo sapiens fibulin 1 (FBLN1), transcript variant D, mRNA | 0.25 |
15. | NM_000956 | Homo sapiens prostaglandin E receptor 2 (subtype EP2), 53kDa (PTGER2), mRNA | 0.26 |
16. | NM_005525 | Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1, mRNA | 0.28 |
17. | NM_173640 | Homo sapiens R-spondin homolog (Xenopus laevis) (RSPO1), transcript variant 2, mRNA. | 0.30 |
18. | NM_001801 | cysteine dioxygenase type1 (CDO1) | 0.30 |
19. | XM_352750 | Homo sapiens collagen, type XIV, alpha 1 (undulin) (COL14A1), mRNA. | 0.31 |
20. | NM_002150 | Homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), mRNA | 0.33 |
21. | NM_001855 | Homo sapiens collagen, type XV, alpha 1 (COL15A1), mRNA. | 0.33 |
22. | XM_166300 | Homo sapiens absent in melanoma 1 (AIM1), mRNA | 0.36 |
23. | NM_005627 | Homo sapiens serum/glucocorticoid regulated kinase (SGK), mRNA | 0.36 |
24. | NM_016564 | Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA. | 0.38 |
25. | NM_133371 | Homo sapiens myozenin 3 (MYOZ3), mRNA | 0.40 |
26. | NM_001290 | Homo sapiens LIM domain binding 2 (LDB2), mRNA. | 0.41 |
27. | NM_003383 | Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 1, mRNA. | 0.43 |
28. | NM_005631 | Homo sapiens smoothened homolog (Drosophila) (SMO), mRNA | 0.43 |
29. | NM_014746 | Homo sapiens ring finger protein 144 (RNF144), mRNA | 0.44 |
30. | NM_000636 | superoxide dismutase 2, mitochondrial (SOD2) | 0.45 |
31. | NM_000690 | aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene encoding mitochondrial protein, mRNA. | 0.48 |
32. | NM_002222 | Homo sapiens inositol 1,4,5-triphosphate receptor, type 1 (ITPR1), mRNA | 0.48 |
33. | NM_012329 | Homo sapiens monocyte to macrophage differentiation-associated (MMD), mRNA. | 0.50 |
34. | NM_000861 | Homo sapiens histamine receptor H1 (HRH1), mRNA | 0.50 |
35. | NM_001353 | aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) | 0.51 |
cDNA of Unknown Biological Function | |||
1. | NM_024563.2 | Homo sapiens chromosome 5 open reading frame 23 (c5orf23)mRNA | 0.48 |
2. | XM_376189.1 | Homo sapiens DKFZP586K1520 protein (DKFZP586K1520), mRNA | 0.41 |
3. | NM_014859.1 | Homo sapiens KIAA0672 gene product (KIAA0672), mRNA. | 0.28 |
4. | XM_352945.1 | Homo sapiens hypothetical protein FLJ37034 (FLJ37034), mRNA | 0.46 |
5. | NM_138409.1 | Homo sapiens chromosome 6 open reading frame 117 (C6orf117), mRNA | 0.21 |