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Table 3 Genes downregulated in palmar fascia fibroblasts obtained from Dupuytren's Contracture using Illumina™ Platform.

From: Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture

  Gene ID Gene Name Fold Change
1. NM_005807 Homo sapiens proteoglycan 4 (PRG4), mRNA. 0.08
2. NM_020299 Homo sapiens aldo-keto reductase family 1, member B10 aldose reductase) (AKR1B10), mRNA. 0.15
3. NM_145176 Homo sapiens solute carrier family 2 (facilitated glucose transporter), member 12 (SLC2A12), mRNA. 0.18
4. NM_001831 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1 0.21
5. NM_012168 F-box protein 2 (FBXO2), mRNA 0.21
6. NM_139125 Homo sapiens mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) (MASP1), transcript variant 2, mRNA. 0.22
7. NM_000691 Homo sapiens aldehyde dehydrogenase 3 family, memberA1 (ALDH3A1), mRNA 0.22
8. NM_178127 Homo sapiens angiopoietin-like 5 (ANGPTL5), mRNA 0.23
9. NM_004000 chitinase-3-like 2 (CHI3L2) 0.22
10. NM_005410 Homo sapiens selenoprotein P, plasma, 1 (SEPP1), mRNA 0.23
11. NM_001996 Homo sapiens fibulin 1 (FBLN1), transcript variant C, mRNA 0.24
12. NM_015714 Homo sapiens G0/G1switch 2 (G0S2), mRNA 0.24
13. NM_021146 angiopoietin-like factor (CDT6) 0.24
14. NM_006486 Homo sapiens fibulin 1 (FBLN1), transcript variant D, mRNA 0.25
15. NM_000956 Homo sapiens prostaglandin E receptor 2 (subtype EP2), 53kDa (PTGER2), mRNA 0.26
16. NM_005525 Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 1, mRNA 0.28
17. NM_173640 Homo sapiens R-spondin homolog (Xenopus laevis) (RSPO1), transcript variant 2, mRNA. 0.30
18. NM_001801 cysteine dioxygenase type1 (CDO1) 0.30
19. XM_352750 Homo sapiens collagen, type XIV, alpha 1 (undulin) (COL14A1), mRNA. 0.31
20. NM_002150 Homo sapiens 4-hydroxyphenylpyruvate dioxygenase (HPD), mRNA 0.33
21. NM_001855 Homo sapiens collagen, type XV, alpha 1 (COL15A1), mRNA. 0.33
22. XM_166300 Homo sapiens absent in melanoma 1 (AIM1), mRNA 0.36
23. NM_005627 Homo sapiens serum/glucocorticoid regulated kinase (SGK), mRNA 0.36
24. NM_016564 Homo sapiens cell cycle exit and neuronal differentiation 1 (CEND1), mRNA. 0.38
25. NM_133371 Homo sapiens myozenin 3 (MYOZ3), mRNA 0.40
26. NM_001290 Homo sapiens LIM domain binding 2 (LDB2), mRNA. 0.41
27. NM_003383 Homo sapiens very low density lipoprotein receptor (VLDLR), transcript variant 1, mRNA. 0.43
28. NM_005631 Homo sapiens smoothened homolog (Drosophila) (SMO), mRNA 0.43
29. NM_014746 Homo sapiens ring finger protein 144 (RNF144), mRNA 0.44
30. NM_000636 superoxide dismutase 2, mitochondrial (SOD2) 0.45
31. NM_000690 aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene encoding mitochondrial protein, mRNA. 0.48
32. NM_002222 Homo sapiens inositol 1,4,5-triphosphate receptor, type 1 (ITPR1), mRNA 0.48
33. NM_012329 Homo sapiens monocyte to macrophage differentiation-associated (MMD), mRNA. 0.50
34. NM_000861 Homo sapiens histamine receptor H1 (HRH1), mRNA 0.50
35. NM_001353 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 0.51
cDNA of Unknown Biological Function
1. NM_024563.2 Homo sapiens chromosome 5 open reading frame 23 (c5orf23)mRNA 0.48
2. XM_376189.1 Homo sapiens DKFZP586K1520 protein (DKFZP586K1520), mRNA 0.41
3. NM_014859.1 Homo sapiens KIAA0672 gene product (KIAA0672), mRNA. 0.28
4. XM_352945.1 Homo sapiens hypothetical protein FLJ37034 (FLJ37034), mRNA 0.46
5. NM_138409.1 Homo sapiens chromosome 6 open reading frame 117 (C6orf117), mRNA 0.21
  1. SAM analysis was performed to identify the statistically significant differentially expressed genes. Genes that are common to both platforms are highlighted as Bold and Italics.