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Table 3 Comparative transcriptomic analysis of normal human epithelial melanocytes to thin primary cutaneous and metastatic melanoma samples

From: The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis

Fold Higher Expression in Melanoma Fold Lower Expression in Melanoma
Gene Symbol NHEM c/t MIS/Thin Gene Symbol NHEM c/t Metastatic Melanoma Gene Symbol NHEM c/t MIS/Thin Gene Symbol NHEM c/t Metastatic Melanoma
KRT14 6787 GJA1 759 MME 106 MAP4 20
GJA1 5929 SEPP1 338 CITED1 77 OCA2 10
EHF 5487 KRT14 306 GDF15 64 TRIM7 7
SCEL 3931 MAGEA2 301 PAEP 47 CITED1 6
CLCA2 3689 TRAG3 242 RPEL1 45 TRPM4 6
S100A7 3609 EHF 193 HES6 43 MME 5
KRTDAP 3416 S100A9 160 ESDN 37 TRAP150 5
DSC1 2782 S100A7 129 QPRT 35 FER1L3 4
GJB6 2576 SCEL 126 OCA2 19 QPRT 4
CXCL14 2484 SLC22A3 125 RENBP 17 KLF8 4
LOR 2308 EPHA3 124 NR4A3 16 RPEL1 4
KRT6A 1989 KRTDAP 121 Siat7c 16 PACE4 4
PKP1 1835 S100A8 120 C6orf168 15 HPCAL1 4
SERPINB3 1778 ZIC1 119 BCL2A1 14 ACTR1A 4
S100A9 1768 CXCL14 118 NTT73 14 MET 3
KRT15 1545 IL18 108 PSCD3 14 RAB32 3
GATA3 1347 PRAME 102 HPCAL1 13 TYR 3
PPL 1339 MAGEA6 94.7 MET 12 IRF6 3
IMUP 1250 PLCB4 88 ALS2CR3 12 GDF15 3
ICEBERG 1123 CLCA2 87 PTPLA 12 HINT3 3
KRT6B 1114 GJB6 85 TBC1D7 11 SLC30A1 3
CSTA 693 MAGEA3 84 OA1 11 TRPV2 3
CST6 687 MMP19 59 TYR 11 RSN 3
  1. NOTE: Abbreviations: NHEM: Normal Human Epithelial Melanocytes, c/t: Compared to, MIS, melanoma-in-situ, Thin, thin melanomas < 1.0 mm in Breslow's thickness