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Table 1 Descriptive Statistics for Study Participants

From: Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites

 

Full Sample (N = 1046)

Subset 1 (N = 330)

Subset 2 (N = 329)

Univariate association with ABI in full sample (N = 1046)

 

Mean (± SD)

Mean (± SD)

Mean (± SD)

β estimate

ABI

1.1 (0.1)

1.1 (0.2)

1.1 (0.1)

 

Age, years

59.1 (10.1)

60.8 (9.1)

61.3 (9.0)

-3.6E-03***

BMI, kg/m2

30.9 (6.2)

31.1 (6.1)

31.9 (6.3)

2.9E-03***

Waist Hip Ratio, cm

0.91 (.11)

0.92 (0.1)

0.92 (0.1)

1.1E01*

SBP, mm Hg

131.1 (16.6)

135.1 (17.4)

135.0 (16.3)

-1.6E-03***

DBP, mm Hg

74.0 (9.0)

74.9 (9.7)

74.5 (9.2)

1.8E-03***

Pulse pressure, mm Hg

57.2 (15.3)

60.2 (15.8)

60.5 (16.1)

-2.5E-03***

Total cholesterol, mg/dL

196.7 (34.9)

193.0 (32.8)

195.2 (33.4)

-2.5E-05

HDL cholesterol, mg/dL

51.4 (14.9)

49.8 (14.3)

50.8 (14.0)

-8.1E-04**

LDL cholesterol, mg/dL

113.8 (31.8)

125.1 (36.5)

126.1 (36.6)

2.8E-04

Triglycerides, mg/dL

159.9 (96.1)

163.8 (97.7)

163.0 (90.0)

-7.4E-05

C-reactive protein, mg/L

0.45 (0.7)

0.50 (0.9)

0.45 (0.5)

-7.2E-03

Fibrinogen, mg/dL

318.3 (77.0)

321.0 (73.6)

324.7 (78.3)

-1.7E-04**

Homocysteine, umol/L

9.9 (2.7)

10.2 (2.8)

10.1 (2.8)

-4.9E-03**

Lp(a), mg/dL

40.1 (38.7)

40.5 (36.5)

40.4 (40.5)

-4.6E-04**

Female, n (%)

580 (55%)

170 (52%)

183 (56%)

-5.4E-02***

Ever smoker, n (%)

528 (51%)

174 (53%)

161 (49%)

-1.4E-02

Diabetes, n (%)

154 (15%)

48(15%)

71(22%)

-2.4E-02

Hypertensive, n (%)

773 (74%)

330 (100%)

329 (100%)

-3.7E-02***

  1. *p < 0.05; ** p < 0.01; *** p < 0.001
  2. ABI, ankle-brachial index; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; HDL, high density lipoprotein; LDL, low density lipoprotein; Lp(a), lipoprotein