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Table 2 Numerical internal scores.

From: Whole genome identification of Mycobacterium tuberculosisvaccine candidates by comprehensive data mining and bioinformatic analyses

Criterion Internal score Maximal score
Macrophage (0) no evidence 3
  (1) significant evidence from one source  
  (2) significant evidence from two sources  
  (3) significant evidence from > two sources + high value  
MprAB (0) no evidence 2
  (1) <3.0 fold expression  
  (2) >3.0 fold expression  
Hypoxia (0) no evidence 2
  (1) 1 evidence  
  (2) >1 evidence, high values  
Reactivation (0) no evidence 2
  (1) evidence from one source  
  (2) evidence from two sources  
Dormancy (0) no evidence 2
  (1) low values  
  (2) high values  
Lung (0) no evidence 2
  (1) evidence from one source  
  (2) multiple evidences (or Rachman/Jain source)  
acr-coregulated (0) no evidence 2
  (2) up regulated  
Secreted (0) no evidence 2
  (1) secreted  
  (2) secreted+virulence-related function  
B-cell immunogen (0) no evidence 2
  (1) evidence from one source  
  (2) multiple evidences  
Iron regulated (0) no evidence 2
  (1) low values  
  (2) high values  
Cell wall (0) not related 2
  (1) general association (without tm)  
  (2) virulence-related function  
Vaccine (0) no evidence 3
  (1) DNA/protein immunization, immune respone but no protection  
  (2) part of a multivalent construct, protection  
  (3) DNA/protein vaccine protection  
Repeats (0) no repeats 2
  (1) repeats only  
  (2) repeats + virulence-related function  
T-cell  
   Experimental (0) no evidence 2
  (1) evidence from one source  
  (2) multiple different evidences  
   Predictions (0) 0< #supertypes <6 2
  (1) 6 < #supertypes <10  
  (2) 10<#supertypes <12