Table 4 Results of pathway profiling using Pathway Express.

1

KEGG

Cell adhesion molecules (CAMs)

6.94

132

11

126

2.099

8.333

9.69E-04

2

KEGG

Axon guidance

6.94

130

11

126

2.099

8.462

9.69E-04

3

KEGG

Leukocyte transendothelial migration

5.288

117

9

113

1.718

7.692

0.005054

4

KEGG

Type I diabetes mellitus

5.232

44

5

40

0.954

11.364

0.005344

5

KEGG

Regulation of actin cytoskeleton

4.461

206

12

198

2.29

5.825

0.011556

6

KEGG

Natural killer cell mediated cytotoxicity

4.11

128

8

114

1.527

6.25

0.016401

7

KEGG

Focal adhesion

3.949

194

11

188

2.099

5.67

0.019276

8

KEGG

Tight junction

3.187

119

7

112

1.336

5.882

0.041314

9

KEGG

Antigen processing and presentation

3.112

86

5

68

0.954

5.814

0.044499

10

KEGG

Adherens junction

2.721

77

5

76

0.954

6.494

0.065823

11

KEGG

Colorectal cancer

2.676

77

5

77

0.954

6.494

0.068828

12

KEGG

Circadian rhythm

2.386

18

2

18

0.382

11.111

0.091979

13

KEGG

Maturity onset diabetes of the young

1.975

25

2

23

0.382

8

0.138816

14

KEGG

VEGF signaling pathway

1.972

72

4

70

0.763

5.556

0.139208

15

KEGG

Fc epsilon RI signaling pathway

1.83

75

4

74

0.763

5.333

0.160493

16

KEGG

mTOR signaling pathway

1.811

49

3

49

0.573

6.122

0.16353

17

KEGG

Huntington's disease

1.558

30

2

30

0.382

6.667

0.210455

18

KEGG

Wnt signaling pathway

1.474

147

6

144

1.145

4.082

0.229071

19

KEGG

MAPK signaling pathway

1.441

273

10

268

1.908

3.663

0.236637

20

KEGG

Toll-like receptor signaling pathway

1.416

91

4

88

0.763

4.396

0.242667

21

KEGG

B cell receptor signaling pathway

1.318

63

3

63

0.573

4.762

0.267565

22

KEGG

T cell receptor signaling pathway

1.294

93

4

93

0.763

4.301

0.274064

23

KEGG

Long-term potentiation

1.235

67

3

66

0.573

4.478

0.290928

24

KEGG

Insulin signaling pathway

1.143

135

5

131

0.954

3.704

0.318761

25

KEGG

Type II diabetes mellitus

1.117

44

2

41

0.382

4.545

0.327167

26

KEGG

Dentatorubropallidoluysian atrophy (DRPLA)

1.044

15

1

15

0.191

6.667

0.352194

27

KEGG

Epithelial cell signaling in Helicobacter pylori infection

0.997

46

2

45

0.382

4.348

0.368822

28

KEGG

Parkinson's disease

0.992

16

1

16

0.191

6.25

0.370684

29

KEGG

Cytokine-cytokine receptor interaction

0.963

256

8

241

1.527

3.125

0.381922

30

KEGG

Jak-STAT signaling pathway

0.936

153

5

144

0.954

3.268

0.392344

31

KEGG

Apoptosis

0.86

84

3

83

0.573

3.571

0.423249

32

KEGG

Complement and coagulation cascades

0.6

69

2

64

0.382

2.899

0.548544

33

KEGG

Olfactory transduction

0.523

31

1

31

0.191

3.226

0.592482

34

KEGG

SNARE interactions in vesicular transport

0.468

36

1

34

0.191

2.778

0.62642

35

KEGG

Phosphatidylinositol signaling system

0.421

79

2

78

0.382

2.532

0.656227

36

KEGG

Taste transduction

0.317

53

1

45

0.191

1.887

0.728441

37

KEGG

GnRH signaling pathway

0.277

97

2

95

0.382

2.062

0.758254

38

KEGG

Gap junction

0.27

99

2

96

0.382

2.02

0.763352

39

KEGG

Adipocytokine signaling pathway

0.145

69

1

69

0.191

1.449

0.864684

40

KEGG

Long-term depression

0.124

75

1

74

0.191

1.333

0.882976

41

KEGG

Neuroactive ligand-receptor interaction

0.102

302

5

279

0.954

1.656

0.902917

42

KEGG

ECM-receptor interaction

0.086

87

1

86

0.191

1.149

0.91743

43

KEGG

Cell cycle

0.042

112

1

110

0.191

0.893

0.958921

44

KEGG

Calcium signaling pathway

0.041

176

2

173

0.382

1.136

0.959904