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Table 1 Distribution of selected characteristics by genotypes for each ABCB1 variant in the Seychelles

From: Association of ABCB1genetic variants with renal function in Africans and in Caucasians

 

2677 G>T

3435 C>T

 

GG

GT

TT

CC

CT

TT

N

191

84

15

132

118

40

Age (years)

46.8 ± 12.2

46.2 ± 11.8

44.6 ± 12.5

46.0 ± 12.2

47.3 ± 11.5

45.8 ± 13.3

Proportion of women

0.57 ± 0.50

0.51 ± 0.50

0.47 ± 0.52

0.59 ± 0.49

0.51 ± 0.50

0.53 ± 0.51

BMIa (kg/m2)

28.0 ± 5.6

28.5 ± 5.0

26.8 ± 4.2

27.3 ± 5.2

29.0 ± 5.7

28.0 ± 4.9

MAPb (mm Hg)

101 ± 13

103 ± 14

98 ± 15

100 ± 14

103 ± 13

99 ± 14

FBGc (mmol/L)

4.6 ± 1.8

4.6 ± 1.7

4.5 ± 1.6

4.6 ± 1.6

4.7 ± 1.9

4.6 ± 1.5

Diabetes (prevalence)

0.08 ± 0.28

0.11 ± 0.31

0.07 ± 0.26

0.08 ± 0.27

0.09 ± 0.29

0.13 ± 0.33

Plasma Na (mmol/L)

140 ± 4

140 ± 4

139 ± 3

140 ± 4

140 ± 4

139 ± 3

Plasma K (mmol/L)

3.8 ± 0.3

3.7 ± 0.3

3.7 ± 0.4

3.7 ± 0.3

3.8 ± 0.3

3.7 ± 0.3

Urine Na (mmol/24 h)

106 ± 54

107 ± 56

104 ± 67

101 ± 54

108 ± 56

118 ± 57

Urine K (mmol/24 h)

44 ± 18

46 ± 18

35 ± 16

44 ± 17

45 ± 19

44 ± 17

  1. Results presented are the mean ± s.d. For each variant, there was no significant trend across genotypes. aBMI: body mass index. bMAP: mean arterial pressure. cFBG: fasting blood glucose.