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Table 1 Distribution of selected characteristics by genotypes for each ABCB1 variant in the Seychelles

From: Association of ABCB1genetic variants with renal function in Africans and in Caucasians

  2677 G>T 3435 C>T
  GG GT TT CC CT TT
N 191 84 15 132 118 40
Age (years) 46.8 ± 12.2 46.2 ± 11.8 44.6 ± 12.5 46.0 ± 12.2 47.3 ± 11.5 45.8 ± 13.3
Proportion of women 0.57 ± 0.50 0.51 ± 0.50 0.47 ± 0.52 0.59 ± 0.49 0.51 ± 0.50 0.53 ± 0.51
BMIa (kg/m2) 28.0 ± 5.6 28.5 ± 5.0 26.8 ± 4.2 27.3 ± 5.2 29.0 ± 5.7 28.0 ± 4.9
MAPb (mm Hg) 101 ± 13 103 ± 14 98 ± 15 100 ± 14 103 ± 13 99 ± 14
FBGc (mmol/L) 4.6 ± 1.8 4.6 ± 1.7 4.5 ± 1.6 4.6 ± 1.6 4.7 ± 1.9 4.6 ± 1.5
Diabetes (prevalence) 0.08 ± 0.28 0.11 ± 0.31 0.07 ± 0.26 0.08 ± 0.27 0.09 ± 0.29 0.13 ± 0.33
Plasma Na (mmol/L) 140 ± 4 140 ± 4 139 ± 3 140 ± 4 140 ± 4 139 ± 3
Plasma K (mmol/L) 3.8 ± 0.3 3.7 ± 0.3 3.7 ± 0.4 3.7 ± 0.3 3.8 ± 0.3 3.7 ± 0.3
Urine Na (mmol/24 h) 106 ± 54 107 ± 56 104 ± 67 101 ± 54 108 ± 56 118 ± 57
Urine K (mmol/24 h) 44 ± 18 46 ± 18 35 ± 16 44 ± 17 45 ± 19 44 ± 17
  1. Results presented are the mean ± s.d. For each variant, there was no significant trend across genotypes. aBMI: body mass index. bMAP: mean arterial pressure. cFBG: fasting blood glucose.